Workshop «Bioactive Peptides and their Photocontrol», Venue: RUS Hotel, 4 Hospitalna str., Kyiv 01601, Ukraine. The workshop was organized by the coordinator, Enamine Ltd. The aim of the workshop was to promote dissemination of the results obtained under the project, exchanging the ideas relevant to peptide-based drug design, and specifically to photopharmacology by photosensitive peptidomimetics. Senior and experienced scientists, the experts in the field of chemistry, biochemistry, pharmacology, attended the event and inspired young talents working under the project. The participants visited Enamine facilities. The…
PELICO Project mid-term meeting was organized by Enamine Ltd. in Kyiv, Ukraine. The meeting agenda can be downloaded here. Project officer Eleftheria Lykouressi and the expert Dr. Julia Maria Alvarez Gutierrez attended the meeting. The coordinator, WP leaders and secondees presented their contribution to the Project and the progress made during the first year of the implementation.
A start-up company Lumobiotics GmbH was founded aiming at translational research into photopharmacology. Strategic partner & seed investor: Enamine Ltd; Partner: BioRN Cluster;
The PELICO Project science featured on a Ukrainian TV broadcasting «Public University», Channel UA1, in front of the students in the studio and many TV viewers, see the video at https://www.youtube.com/watch?v=eKdJeMuGl7I
Research pharmacokinetic and toxicity studies of the photoswitchable gramicidin S analogues on mice was finished at Bienta for Enamine under the PELICO Project. Valuable experience on working with photosensitive drugs, their laser activation in tissue (see the photo below) and subsequent analysis of samples was acquired. The studies confirmed the preliminary data published earlier by us in Angewandte Chemie (DOI: 10.1002/anie.201600506) and found new results which are very encouraging for the use of the peptidomimetics in photodynamic therapy of cancer.
Senior Latvian Institute of Organic Synthesis leaders visited Enamine and Ukrorgsyntez. They met with the colleagues from Ukraine and discussed prospects of further cooperation as well as current results on the Project. On the photo below, from left to right: Chairman of the Scientific Board of the Latvian Institute of Organic Synthesis Prof. Ivars Kalvins; Director of Ukrorgsyntez Dr. Sergii Dovgopolyi; PELICO Project coordinator at Latvian Institute of Organic Synthesis Prof. Aigars Jirgensons; Director of Latvian Institute of Organic Synthesis Prof. Osvalds Pugovics. In an…
The scientists involved in the PELICO Project began the research into cytotoxic photosensitive compounds, analogues of the known antibiotic sramicidin S (Angewandte Chemie, DOI: 10.1002/anie.201600506).